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A research study in rats reported that another GLP-1 medication with similar effects to tirzepatide, Saxenda (liraglutide), lowered wakefulness and modified the rats sleep patterns

Weight regain after stopping GLP-1 medications typically begins within 13 weeks of discontinuation, with research showing most patients return to baseline weight within 612 months

Categorical variables were summarized with frequencies and percentages

These sources report trials conducted with FDA-approved branded semaglutide

Anti-inflammatory effect of glucagon-like peptide-1 receptor agonist on the neurosensory retina in an acute optic nerve injury rat model

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